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KCTD15

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Protein-coding gene in the species Homo sapiens
KCTD15
Identifiers
AliasesKCTD15, potassium channel tetramerization domain containing 15
External IDsOMIM: 615240; MGI: 2385276; HomoloGene: 11450; GeneCards: KCTD15; OMA:KCTD15 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)
Chromosome 19 (human)Genomic location for KCTD15Genomic location for KCTD15
Band19q13.11Start33,795,933 bp
End33,815,763 bp
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)
Chromosome 7 (mouse)Genomic location for KCTD15Genomic location for KCTD15
Band7|7 B1- B2Start34,338,439 bp
End34,356,157 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • ventricular zone

  • ganglionic eminence

  • left uterine tube

  • skin of hip

  • skin of abdomen

  • right coronary artery

  • body of uterus

  • skin of leg

  • ectocervix

  • human penis
Top expressed in
  • otic vesicle

  • hand

  • lip

  • foot

  • triceps brachii muscle

  • vastus lateralis muscle

  • medial head of gastrocnemius muscle

  • sternocleidomastoid muscle

  • skeletal muscle tissue

  • temporal muscle
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

79047

233107

Ensembl

ENSG00000153885

ENSMUSG00000030499

UniProt

Q96SI1

Q8K0E1

RefSeq (mRNA)

NM_001129994
NM_001129995
NM_024076

NM_146188
NM_001360818
NM_001360820

RefSeq (protein)

NP_001123466
NP_001123467
NP_076981

NP_666300
NP_001347747
NP_001347749

Location (UCSC)Chr 19: 33.8 – 33.82 MbChr 7: 34.34 – 34.36 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Potassium channel tetramerisation domain containing 15 also known as BTB/POZ domain-containing protein KCTD15 is protein that in humans is encoded by the KCTD15 gene.

Clinical significance

Variants of the KCTD15 gene may be associated with obesity.

See also

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000153885Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000030499Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Strausberg RL, Feingold EA, Grouse LH, et al. (December 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  6. Thorleifsson G, Walters GB, Gudbjartsson DF, et al. (January 2009). "Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity". Nat. Genet. 41 (1): 18–24. doi:10.1038/ng.274. PMID 19079260. S2CID 764409.
  7. Willer CJ, Speliotes EK, Loos RJ, et al. (January 2009). "Six new loci associated with body mass index highlight a neuronal influence on body weight regulation". Nat. Genet. 41 (1): 24–34. doi:10.1038/ng.287. PMC 2695662. PMID 19079261.
  8. Zhao J, Bradfield JP, Li M, et al. (May 2009). "The role of obesity-associated loci identified in genome wide association studies in the determination of pediatric BMI". Obesity (Silver Spring). 17 (12): 2254–7. doi:10.1038/oby.2009.159. PMC 2860782. PMID 19478790.

Further reading


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