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Kappadione

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Chemical compound Pharmaceutical compound
Kappadione
Clinical data
Routes of
administration		Injection
ATC code
  • none
Legal status
Legal status
  • US: Rx only, discontinued (was FDA approved)
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • Tetrasodium (2-methyl-4-phosphonatooxynaphthalen-1-yl) phosphate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.004.558 Edit this at Wikidata
Chemical and physical data
FormulaC11H8Na4O8P2
Molar mass422.084 g·mol
3D model (JSmol)
SMILES
  • CC1=C(C2=CC=CC=C2C(=C1)OP(=O)())OP(=O)()....
InChI
  • InChI=1S/C11H12O8P2.4Na/c1-7-6-10(18-20(12,13)14)8-4-2-3-5-9(8)11(7)19-21(15,16)17;;;;/h2-6H,1H3,(H2,12,13,14)(H2,15,16,17);;;;/q;4*+1/p-4
  • Key:GZBACHSOZNEZOG-UHFFFAOYSA-J
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Kappadione is a vitamin K derivative used for the treatment of side effects of vitamin K antagonists such as warfarin, prophylaxis and treatment of vitamin K deficiency bleeding, and hypoprothrombinemia due to various causes. It was manufactured by Eli Lilly and Company. Chemically, it is menadiol sodium diphosphate. It was approved by the US Food and Drug Administration prior to 1982 and marketed by Lilly. It has since been discontinued and is not available in North America.

References

  1. ^ DrugBank DB09332 . Accessed 21 April 2021.
  2. "Kappadione overview, medicine.org". Archived from the original on 2016-03-03. Retrieved 2008-04-14.


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