Kouassi is a surname. Notable people with the surname include:
- Blaise Kouassi (footballer, born 1974), former Côte d'Ivoire football defender
- Blaise Kouassi (footballer, born 1983), Ivorian footballer
- Desmond N'Ze Kouassi (or Desmond N'Ze) (born 1989), Ghanaian footballer
- Euphrasie Kouassi Yao (born 1964), Ivorian politician
- Gervais Lombe Yao Kouassi known as Gervinho (born 1987), Ivorian footballer
- Jean Evrard Kouassi (born 1994), Ivorian footballer
- Marcus N'Ze Kouassi known as Marcus N'Ze (born 1987), Ghanaian footballer
- Martial Yao Kouassi (or Martial Yao) (born 1989), Ivorian footballer
- Venceslas Kouassi (born 1981), Ivorian-born Burkinabé footballer
- Victor Kouassi (born 1971), Ivorian rugby union player
- Xavier Kouassi (born 1989), Ivorian-Swiss footballer
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