L-arabinitol 4-dehydrogenase | |||||||||
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L-arabinitol 4-dehydrogenase homotetramer, Neurospora crassa | |||||||||
Identifiers | |||||||||
EC no. | 1.1.1.12 | ||||||||
CAS no. | 9028-19-7 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a L-arabinitol 4-dehydrogenase (EC 1.1.1.12) is an enzyme that catalyzes the chemical reaction
- L-arabinitol + NAD L-xylulose + NADH + H
Thus, the two substrates of this enzyme are L-arabinitol and NAD, whereas its 3 products are L-xylulose, NADH, and H.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is L-arabinitol:NAD 4-oxidoreductase (L-xylulose-forming). Other names in common use include pentitol-DPN dehydrogenase, and L-arabitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions.
References
- Chiang C, Knight SG (1960). "A new pathway of pentose metabolism". Biochem. Biophys. Res. Commun. 3 (5): 554–9. doi:10.1016/0006-291X(60)90174-1. PMID 13692998.
- Chiang C, Knight SG (1961). "L-Arabinose metabolism by cell-free extracts of Penicillium chrysogenum". Biochim. Biophys. Acta. 46 (2): 271–8. doi:10.1016/0006-3002(61)90750-8. PMID 13692999.
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