| L-methionine (R)-S-oxide reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.8.4.14 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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In enzymology, a L-methionine (R)-S-oxide reductase (EC 1.8.4.14) is an enzyme that catalyzes the chemical reaction
- L-methionine + thioredoxin disulfide + H2O L-methionine (R)-S-oxide + thioredoxin
L-methionine (R)-S-oxide + thioredoxinThe 3 substrates of this enzyme are L-methionine, thioredoxin disulfide, and H2O, whereas its two products are L-methionine (R)-S-oxide and thioredoxin.
This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with a disulfide as acceptor. The systematic name of this enzyme class is L-methionine:thioredoxin-disulfide S-oxidoreductase . Other names in common use include fRMsr, FRMsr, free met-R-(o) reductase, and free-methionine (R)-S-oxide reductase. This enzyme participates in methionine metabolism.
References
- Etienne F, Spector D, Brot N, Weissbach H (2003). "A methionine sulfoxide reductase in Escherichia coli that reduces the R enantiomer of methionine sulfoxide". Biochem. Biophys. Res. Commun. 300 (2): 378–82. doi:10.1016/S0006-291X(02)02870-X. PMID 12504094.
| Oxidoreductases: sulfur oxidoreductases (EC 1.8) | |
|---|---|
| 1.8.1: NAD or NADP | |
| 1.8.2: cytochrome | |
| 1.8.3: oxygen | |
| 1.8.4: disulfide | |
| 1.8.5: quinone | |
| 1.8.98: Other, known | |
| 1.8.99: Other | |
| Enzymes | |
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| Activity | |
| Regulation | |
| Classification | |
| Kinetics | |
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