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LRP3
Identifiers
Aliases	LRP3, LDL receptor related protein 3
External IDs	OMIM: 603159; MGI: 3584516; HomoloGene: 1745; GeneCards: LRP3; OMA:LRP3 - orthologs
Gene location (Human) Chr. Chromosome 19 (human) Band 19q13.11 Start 33,177,603 bp End 33,208,864 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 B2 Start 34,899,452 bp End 34,914,923 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in putamen nucleus accumbens caudate nucleus left ovary superior frontal gyrus Temporal Lobe right frontal lobe Amygdala primary visual cortex prefrontal cortex Top expressed in primary visual cortex superior frontal gyrus ventricular zone dentate gyrus of hippocampal formation granule cell cerebellar cortex genital tubercle ganglionic eminence right kidney tail of embryo neural layer of retina More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 4037 435965 Ensembl ENSG00000130881 ENSMUSG00000001802 UniProt O75074 n/a RefSeq (mRNA) NM_002333 NM_001024707 RefSeq (protein) NP_002324 n/a Location (UCSC) Chr 19: 33.18 – 33.21 Mb Chr 7: 34.9 – 34.91 Mb PubMed search
Wikidata
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Low density lipoprotein receptor-related protein 3 (LRP-3) is a protein that in humans is encoded by the LRP3 gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000130881 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000001802 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Low density lipoprotein receptor-related protein 3". Retrieved 2011-10-05.

Further reading

• Takatsu H, Katoh Y, Shiba Y, Nakayama K (Jul 2001). "Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains". The Journal of Biological Chemistry. 276 (30): 28541–5. doi:10.1074/jbc.C100218200. PMID 11390366.
• Korenberg JR, Argraves KM, Chen XN, Tran H, Strickland DK, Argraves WS (Jul 1994). "Chromosomal localization of human genes for the LDL receptor family member glycoprotein 330 (LRP2) and its associated protein RAP (LRPAP1)". Genomics. 22 (1): 88–93. doi:10.1006/geno.1994.1348. PMID 7959795.
• Ishii H, Kim DH, Fujita T, Endo Y, Saeki S, Yamamoto TT (Jul 1998). "cDNA cloning of a new low-density lipoprotein receptor-related protein and mapping of its gene (LRP3) to chromosome bands 19q12-q13. 2". Genomics. 51 (1): 132–5. doi:10.1006/geno.1998.5339. PMID 9693042.

v t e Lipids: lipoprotein particle metabolism
Lipoprotein particle classes and subclasses	delivery of TGs: Chylomicron VLDL delivery of C and CE: IDL LDL lb LDL sd LDL Lp(a) HDL Remnant cholesterol
Apolipoproteins	APOA 1 2 4 5 APOB APOC 1 2 3 4 APOD APOE APOH SAA SAA1
Extracellular enzymes	LCAT LIPC LPL
Lipid transfer proteins	CETP MTTP PLTP
Cell surface receptors	HDL: SCARB1 IDL: LRP LRP1 LRP1B LRP2 LRP3 LRP4 LRP5 LRP5L LRP6 LRP8 LRP10 LRP11 LRP12 LDL: LDLR LRPAP1
ATP-binding cassette transporter	ABCA1 ABCG5 ABCG8

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