Misplaced Pages

LRRK1

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.

Protein-coding gene in the species Homo sapiens
LRRK1
Identifiers
AliasesLRRK1, RIPK6, Roco1, leucine-rich repeat kinase 1, leucine rich repeat kinase 1, OSMD
External IDsOMIM: 610986; MGI: 2142227; HomoloGene: 23464; GeneCards: LRRK1; OMA:LRRK1 - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)
Chromosome 15 (human)Genomic location for LRRK1Genomic location for LRRK1
Band15q26.3Start100,919,327 bp
End101,078,257 bp
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)
Chromosome 7 (mouse)Genomic location for LRRK1Genomic location for LRRK1
Band7|7 CStart65,876,660 bp
End66,038,098 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • lymph node

  • appendix

  • transverse colon

  • spleen

  • monocyte

  • mucosa of transverse colon

  • minor salivary glands

  • skin of leg

  • rectum

  • stromal cell of endometrium
Top expressed in
  • right lung lobe

  • transitional epithelium of urinary bladder

  • left lung

  • medullary collecting duct

  • left lung lobe

  • endothelial cell of lymphatic vessel

  • conjunctival fornix

  • mesenteric lymph nodes

  • stroma of bone marrow

  • epithelium of stomach
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

79705

233328

Ensembl

ENSG00000154237

ENSMUSG00000015133

UniProt

Q38SD2

Q3UHC2

RefSeq (mRNA)

NM_024652
NM_001039843

NM_146191

RefSeq (protein)

NP_078928

NP_666303

Location (UCSC)Chr 15: 100.92 – 101.08 MbChr 7: 65.88 – 66.04 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Leucine-rich repeat serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the LRRK1 gene.


References

  1. ^ GRCh38: Ensembl release 89: ENSG00000154237Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000015133Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Nagase T, Nakayama M, Nakajima D, Kikuno R, Ohara O (May 2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 8 (2): 85–95. doi:10.1093/dnares/8.2.85. PMID 11347906.
  6. Bosgraaf L, Van Haastert PJ (Dec 2003). "Roc, a Ras/GTPase domain in complex proteins" (PDF). Biochim Biophys Acta. 1643 (1–3): 5–10. doi:10.1016/j.bbamcr.2003.08.008. PMID 14654223. S2CID 45525061.
  7. "Entrez Gene: LRRK1 leucine-rich repeat kinase 1".

Further reading


Stub icon

This article on a gene on human chromosome 15 is a stub. You can help Misplaced Pages by expanding it.

Categories: