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Allmusic found that "more than any other recording issued by this excellent band, Leucocyte captures the art of music making at the moment of conception." PopMatters said that the album "is refreshing if not always easy or fun listening. E.S.T. could have continued making contemplative or gospel-tinged acoustic jazz in the Jarrett/ECM mode (the brief “Ajar” here is a fine example), but Svensson and his group have been frying bigger fish from the start."