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Lichen ruber moniliformis, also known as morbus moniliformis lichenoide, Wise-Rein disease, Nekam disease, keratosis lichenoides chronica, is a rare skin disease named for Fred Wise and Charles R. Rein.
It is one of several diseases also known as Kaposi's disease, based on its characterization in 1886 by Moritz Kaposi.
Presentation
The disease causes numerous whitish punctiform papules and brownish macules arranged in a necklace-like pattern.
Diagnosis
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Treatment
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F. Wise, C. R. Rein. Lichen ruber moniliformis (morbus moniliformis lichenoides). Report of a case and description of a hitherto unrecorded histologic structure. Archives of Dermatology and Syphilology, Chicago, 1936, 34: 830-849.
M. Kaposi. Lichen ruber moniliformis. Vierteljahrsschrift für Dermatologie und Syphilis, Wien, 1886, 13: 571-582.