The Rectors of the College of Europe:
- Hendrik Brugmans (1950–1972)
- Jerzy Łukaszewski (1972–1990)
- Werner Ungerer (1990–1993)
- Gabriel Fragnière (1993–1995)
- Otto von der Gablentz (1996–2001)
- Piet Akkermans (2001–2002)
- Robert Picht (Rector ad interim) (2002 – 31 January 2003)
- Paul Demaret (2003–2013)
- Jörg Monar (2013–2020)
- Federica Mogherini (2020-)
A second campus was opened at the invitation of the Polish government in Natolin (Warsaw) in 1992. Vice-rectors of the College of Europe's Natolin (Warsaw) campus:
- Ettore Deodato (1993)
- David W. Lewis (1994–1996)
- Jacek Saryusz-Wolski (1996–1999)
- Piotr Nowina-Konopka (1999–2004)
- Robert Picht (Vice-Rector ad interim) (2004–2005)
- Robert Picht (2005–2007)
- Ewa Ośniecka-Tamecka (2007–)