Notable present and past Lehigh University faculty include:
- Ferdinand P. Beer
- Michael Behe
- Donald T. Campbell
- Huai-Dong Cao
- Fazıl Erdoğan - Member of the National Academy of Engineering
- Maurice Ewing
- Dan M. Frangopol
- Lawrence H. Gipson
- Joseph I. Goldstein
- John Grogan
- John E. Hare
- Joachim Grenestedt
- Terry Hart
- Daniel Chonghan Hong
- Thomas Hyclak
- George Rankine Irwin
- Stanley J. Jaworski
- Derrick Henry Lehmer
- Alexander Macfarlane
- Gordon Moskowitz
- Ronald Rivlin
- Miles Rock graduated in the first class from Lehigh in 1869. Notable for helping define the Guatemalan and Mexican border.
- Rajan Menon
- Dork Sahagian- Nobel Laureate
- Greg Strobel
- Miranda Teboh-Ewungkem
- André Weil
- Ricardo Viera
- Stephanie Powell Watts
- George D. Watkins, member of the National Academy of Sciences
- Albert Wilansky, discoverer of the mathematical property of Smith numbers through his brother-in-law Harold Smith's phone number, 493-7775
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