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This is the list of Schedule IV controlled substances in the United States as defined by the Controlled Substances Act. The following findings are required for substances to be placed in this schedule:

1. The drug or other substance has a low potential for abuse relative to the drugs or other substances in schedule III.
2. The drug or other substance has a currently accepted medical use in treatment in the United States.
3. Abuse of the drug or other substance may lead to limited physical dependence or psychological dependence relative to the drugs or other substances in schedule III.

The complete list of Schedule IV substances is as follows. The Administrative Controlled Substances Code Number and Federal Register citation for each substance is included.

Narcotics

Depressants

Flunitrazepam has not been approved by the Food and Drug Administration for medical use, and is considered to be an illegal drug.

Temazepam may require a specially coded prescription in certain States.

Lorcaserin

Stimulants

Others

See also

• List of Schedule I controlled substances (U.S.)
• List of Schedule II controlled substances (U.S.)
• List of Schedule III controlled substances (U.S.)
• List of Schedule V controlled substances (U.S.)

Notes

1. ^ This substance was expressly scheduled by the Controlled Substances Act on October 27, 1970. The 1974 Federal Register ruling (by Administrator John R. Bartels, Jr.) merely organized its listing in the Code of Federal Regulations.

References

1. "21 CFR 1308.14 (Schedule IV)". Code of Federal Regulations. Retrieved September 9, 2023.
2. 21 U.S.C. § 812(b)(4) retrieved October 2, 2007
3. Bensinger, Peter (August 28, 1978). "Placement of Preparations Containing Difenoxin in Combination With Atropine Sulfate Into Schedules IV and V" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
4. Bensinger, Peter (July 24, 1980). "Classification of Dextropropoxyphene as a Narcotic Drug in Schedule IV of the Controlled Substances Act" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
5. Harrigan, Thomas (July 2, 2014). "Schedules of Controlled Substances: Placement of Tramadol Into Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
6. Leonhart, Michele (February 27, 2014). "Schedules of Controlled Substances: Placement of Alfaxalone into Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
7. Mullen, Jr., Francis M. (November 12, 1981). "Schedules of Controlled Substsnces; Placement of Alprazolam in Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
8. ^ Bartels Jr., John R. (June 20, 1974). "PART 1308— SCHEDULES OF CONTROLLED SUBSTANCES: Annual Publication" (PDF). Government Publishing Office. Drug Enforcement Administration. Archived from the original (PDF) on September 6, 2023. Retrieved September 6, 2023.
9. Dhillon, Uttam (January 24, 2020). "Schedules of Controlled Substances: Placement of Brexanolone in Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved September 6, 2023.
10. ^ Mullen, Jr., Francis M. (October 5, 1984). "Schedules of Controlled Substances; Temporary Placement of Bromazepam, Camazepam, Clobazam, Clotiazepam, Cloxazolam, Delorazepam, Estazolam, Ethyl Loflazepate, Fludiazepam, Flunitrazepam, Haloxazolam, Ketazolam, Loprazolam, Lormetazepam, Medazepam, Nimetazepam, Nitrazepam, Nordiazepam, Oxazolam, Pinazepam, and Tetrazepam Into Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
11. Leonhart, Michele (December 12, 2011). "Schedules of Controlled Substances: Placement of Carisoprodol Into Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
12. ^ Bartels, Jr., John R. (May 28, 1975). "Schedules of Controlled Substances; Placement of Chlordiazepoxide, Diazepam, Oxazepam, Chlorazepate, Flurazepam, and Clonazepam into Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
13. Milgram, Anne (April 7, 2022). "Schedules of Controlled Substances: Placement of Daridorexant in Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
14. Simpkins, William (August 16, 2001). "Schedules of controlled substances: Dichloralphenazone; placement into Schedule IV". VLEX. Drug Enforcement Administration. Archived from the original on January 16, 2023. Retrieved January 16, 2023.
15. Leonhart, Michele (October 6, 2009). "Schedules of Controlled Substances; Placement of Fospropofol Into Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
16. Mullen, Jr., Francis M. (October 29, 1981). "Schedules of Controlled Substances: Placement of Halazepam in Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
17. Evans, D. Christopher (March 3, 2021). "Schedules of Controlled Substances: Placement of Lemborexant in Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
18. Bensinger, Peter (October 7, 1977). "Placement of Lorazepam in Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
19. Bartels, Jr., John R. (January 30, 1975). "Placement of Mebutamate in Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2022.
20. ^ Lawn, John (March 25, 1986). "Schedules of Controlled Substances; Placement of Quazepam and Midazolam into Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
21. Bensinger, Peter (December 17, 1976). "Placement of Prazepam into Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
22. Evans, D. Christopher (July 2, 2021). "Schedules of Controlled Substances: Placement of Remimazolam in Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved September 6, 2023.
23. Harrigan, Thomas (August 28, 2014). "Schedules of Controlled Substances: Placement of Suvorexant into Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
24. Bensinger, Peter (April 7, 1981). "Schedules of Controlled Substances; Placement of Temazepam into Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
25. Mullen, Jr., Francis M. (December 28, 1982). "Schedules of Controlled Substances; Placement of Triazolam into Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
26. Marshall, Donnie (September 15, 1999). "Schedules of Controlled Substances; Placement of Zaleplon into Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
27. Bonner, Robert (February 5, 1993). "Schedules of Controlled Substances; Placement of Zolpidem into Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on March 3, 2022. Retrieved January 16, 2023.
28. Leonhart, Michele (April 4, 2005). "Schedules of Controlled Substances: Placement of Zopiclone Into Schedule IV". Federal Register. Drug Enforcement Administration.
29. Milgram, Anne (October 31, 2023). "Schedules of Controlled Substances: Placement of Zuranolone in Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved November 3, 2023.
30. Leonhart, Michele (May 8, 2013). "Schedules of Controlled Substances: Placement of Lorcaserin Into Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
31. ^ Lawn, John (May 17, 1988). "Schedules of Controlled Substances; Temporary Placement of Cathine ((+ )-norpseudoephedrine), Fencamfamin, Fenproporex and Mefenorex Into Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on March 3, 2022. Retrieved January 16, 2023.
32. ^ Ingersoll, John (July 6, 1973). "Diethylpropion and Phentermine; Temporary Placement in Schedule IV" (PDF). Isomer Design. Bureau of Narcotics and Dangerous Drugs. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
33. Mullen, Jr., Francis M. (October 27, 1981). "Rescheduling of Mazindol into Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on September 26, 2021. Retrieved January 16, 2023.
34. Marshall, Donnie (January 27, 1999). "Schedules of Controlled Substances: Placement of Modafinil Into Schedule IV". Federal Register. Drug Enforcement Administration.
35. Bartels, Jr., John R. (January 28, 1975). "Placement of Pemoline in Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
36. ^ Bensinger, Peter (September 30, 1980). "Pipradrol and SPA in Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
37. Milgram, Anne (July 25, 2022). "Schedules of Controlled Substances: Placement of Serdexmethylphenidate in Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved September 6, 2023.
38. Gruden, Peter (February 11, 1998). "Schedules of Controlled Substances: Placement of Sibutramine Into Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
39. Dhillon, Uttam (January 7, 2020). "Schedules of Controlled Substances: Placement of Solriamfetol in Schedule IV". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
40. Bensinger, Peter (February 9, 1979). "Placement of Pentazocine into Schedule IV" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
41. Milford, Jr., James S. (October 31, 1997). "Schedules of Controlled Substances Placement of Butorphanol Into Schedule IV". Federal Register. Drug Enforcement Administration. Archived from the original on January 16, 2023. Retrieved January 16, 2023.
42. Rosenberg, Chuck (November 12, 2015). "Schedules of Controlled Substances: Placement of Eluxadoline Into Schedule IV". Federal Register. Drug Enforcement Administration. Archived from the original on January 16, 2023. Retrieved January 16, 2023.

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