List of cutaneous neoplasms associated with systemic syndromes

This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources.

Many cutaneous neoplasms occur in the setting of systemic syndromes.

Cutaneous neoplasms associated with systemic syndromes
Neoplasm	Associated syndrome(s)
Trichoepithelioma	Brooke–Spiegler syndrome Rombo syndrome Rasmussen syndrome Brooke–Fordyce syndrome Bazex–Dupré–Christol syndrome
Cylindroma	Brooke–Spiegler syndrome Rasmussen syndrome
Psammomatous melanotic schwannoma	Carney complex
Sclerotic fibroma	Cowden syndrome
Trichilemmoma	Cowden syndrome Bannayan–Riley–Ruvalcaba syndrome
Sebaceous adenoma	Muir–Torre syndrome
Sebaceous carcinoma	Muir–Torre syndrome
Syringofibroadenoma	Clouston syndrome Schöpf–Schulz–Passarge syndrome
Syringoma	Down syndrome Nicolau–Balus syndrome Brooke–Spiegler syndrome
Trichodiscoma	Birt–Hogg–Dubé syndrome
Hidrocystoma	Schöpf–Schulz–Passarge syndrome
Pilomatricoma	Turner syndrome
Poroma	Schöpf–Schulz–Passarge syndrome Clouston syndrome
Spiradenoma	Brooke–Spiegler syndrome
Fibrofolliculoma	Birt–Hogg–Dubé syndrome
Clear cell acanthoma	Ichthyosis
Acrochordon	Birt–Hogg–Dubé syndrome
Epidermal inclusion cyst with pilomatrical differentiation	Gardner's syndrome
Gardner fibroma	Familial adenomatous polyposis and its variant, Gardner's syndrome
Dermoid tumor	Familial adenomatous polyposis and its variant, Gardner's syndrome

References

Uede K, Yamamoto Y, Furukawa F. Brooke-Spiegler syndrome associated with cylindroma, trichoepithelioma, spiradenoma, and syringoma. J Dermatol. Jan 2004;31(1):32-8.
Prevalence of Pilomatricoma in Turner Syndrome: Findings From a Multicenter Study. Handler MZ, Derrick KM, Lutz RE, Morrell DS, Davenport ML, Armstrong AW. JAMA Dermatol. 2013 Feb 20:1-6. doi:10.1001/2013.jamadermatol.115. PMID 23426075
^ Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck". Head and Neck Pathology. 14 (1): 43–58. doi:10.1007/s12105-019-01104-3. PMC 7021862. PMID 31950474.

Bolognia, Jean L.; et al. (2007). Dermatology. St. Louis: Mosby. ISBN 1-4160-2999-0.
James, William D.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.

J Am Acad Dermatol. 1983 May;8(5):639-44. Pilomatricoma-like changes in the epidermal cysts of Gardner's syndrome. Cooper PH, Fechner RE.