Hepato-biliary diseases include liver diseases and biliary diseases. Their study is known as hepatology.
Liver diseases
Further information: Chronic liver diseaseViral hepatitis
- Acute hepatitis A
- Acute hepatitis B
- Acute hepatitis C
- Acute hepatitis D – this is a superinfection with the delta-agent in a patient already infected with hepatitis B
- Acute hepatitis E
- Chronic viral hepatitis
- Other viral hepatitis viruses may exist but their relation to the disease is not firmly established like the previous ones (hepatitis F, GB virus C, hepatitis X)
Other infectious diseases
- Hepatitis:
- cytomegalovirus infection
- herpesviral: herpes simplex infection
- Toxoplasmosis
- Hepatosplenic schistosomiasis
- Portal hypertension in schistosomiasis
- Liver disease in syphilis
- Epstein–Barr virus infection
- yellow fever virus infection
- rubella virus infection
- leptospirosis
- Echinococcosis
- Amoebiasis
Other inflammatory diseases
- liver abscess
- autoimmune hepatitis
- primary biliary cholangitis (primary biliary cirrhosis)
- phlebitis of the portal vein
- granulomatous hepatitis
- nonalcoholic steatohepatitis (NASH)
Alcohol
This may cause fatty liver, hepatitis, fibrosis and sclerosis leading to cirrhosis and finally liver failure.
Toxins
This includes mostly drug-induced hepatotoxicity, (DILI) which may generate many different patterns over liver disease, including
- cholestasis
- necrosis
- acute hepatitis and chronic hepatitis of different forms,
- cirrhosis
- Effects of Acetaminophen (Tylenol)
- other rare disorders like focal nodular hyperplasia, Hepatic fibrosis, peliosis hepatis and veno-occlusive disease.
Liver damage is part of Reye syndrome.
Tumours
Malignant neoplasm of liver and intrahepatic bile ducts. The most frequent forms are metastatic malignant neoplasm of liver)
- liver cell carcinoma
- cholangiocarcinoma
- hepatoblastoma
- angiosarcoma of liver
- Kupffer cell sarcoma
- other sarcomas of liver
Benign neoplasm of liver include hepatic hemangiomas, hepatic adenomas, and focal nodular hyperplasia (FNH).
End-stage liver disease
Chronic liver diseases like chronic hepatitis, chronic alcohol abuse or chronic toxic liver disease may cause
- liver failure and hepatorenal syndrome
- fibrosis and cirrhosis of liver
Cirrhosis may also occur in primary biliary cirrhosis. Rarely, cirrhosis is congenital.
Metabolic diseases
- metabolic diseases (chapter E in ICD-10)
Vascular disorders
- chronic passive congestion of liver
- central haemorrhagic necrosis of liver
- infarction of liver
- peliosis hepatis
- veno-occlusive disease
- portal hypertension
- Budd–Chiari syndrome
Cysts
- Congenital cystic disease of the liver
- Cysts caused by Echinococcus
- Polycystic liver disease
Others
Amyloid degeneration of liver
Gallbladder and biliary tract diseases
- malignant neoplasm of the gallbladder
- malignant neoplasm of other parts of biliary tract
- extrahepatic bile duct
- ampulla of Vater
- cholelithiasis
- cholecystitis
- others (excluding postcholecystectomy syndrome), but including
- other obstructions of the gallbladder (like strictures)
- hydrops, perforation, fistula
- cholesterolosis
- biliary dyskinesia
- ICD-10 code K83: other diseases of the biliary tract:
- cholangitis (including ascending cholangitis and primary sclerosing cholangitis)
- obstruction, perforation, fistula of biliary tract (bile duct)
- spasm of sphincter of Oddi
- biliary cyst
- biliary atresia
References
ICD-10 codes K70-K77: Liver Diseases
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Upper GI tract |
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Lower GI tract Enteropathy |
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Other |
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