The city of Syracuse, on the island of Sicily southwest of the Italian peninsula, has been besieged repeatedly since its founding as a Greek colony, including the following:
- Before the Common Era, while a Greek colony or Hellenistic state:
- 415–413 by the Athenians during the Sicilian Expedition
- 397 by the Carthaginians
- 343 by Hicetas, the Carthaginians and Timoleon
- 311–09 by the Carthaginians
- 278 by the Carthaginians
- 214–2 by the Roman Republic during the Second Punic War (and subject of film L'Assedio di Siracusa)
- In the Common Era, while a Byzantine province, by the Aghlabids:
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