Lucchini is an Italian surname. It may refer to:
- People
- Alessia Lucchini (born 1978), Italian former synchronized swimmer
- Antonio Maria Lucchini, Italian librettist
- Arsène Lucchini (1922–1998), French ski jumper
- Aurelio Lucchini, Uruguayan architectural historian
- Florian Lucchini, French football player
- Franco Lucchini, Italian World War II pilot
- Giovanni Francesco Lucchini, Italian architect
- Giuseppe Lucchini (born 1952), Italian businessman
- Italia Lucchini (1918 – unknown), Italian sprinter
- Jake Lucchini (born 1995), Canadian ice hockey player
- Leo Oswald Lucchini (1927–1991), Canadian ice hockey player
- Luigi Lucchini, Italian businessman
- Stefano Lucchini, Italian football player
- Vincenzo Lucchini (1925–1984), Swiss former sports shooter
- Companies
- Gruppo Lucchini, an Italian steel company
- Lucchini Engineering, an Italian sports car constructor and racing team
- Lucchini RS, an Italian company
- Fictional characters
- Francesca Lucchini in the cast of Strike Witches, created by Humikane Shimada
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