Luer (also Lüer) is a Germanic surname. It may refer to:
- Carlyle A. Luer (born 1922), American botanist specializing in orchids
- Greg Luer (born 1994), English footballer
- Hermann Wülfing Luer (?–1883), German instrument maker; inventor of the Luer taper
- Hugo Gunckel Lüer (1901–1997), Chilean pharmacist, botanist, and university professor
- Karl-Hermann Lüer (1933–2014), German saxophonist and flautist
- Ludwig Luer (fl. WWI-era), German flying ace
See also
- Luer taper, a system for making leak-free connections between pieces of medical or laboratory equipment
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