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LCLAT1
Identifiers
Aliases	LCLAT1, 1AGPAT8, AGPAT8, ALCAT1, HSRG1849, LYCAT, UNQ1849, lysocardiolipin acyltransferase 1
External IDs	OMIM: 614241; MGI: 2684937; HomoloGene: 33167; GeneCards: LCLAT1; OMA:LCLAT1 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2p23.1 Start 30,447,226 bp End 30,644,225 bp
Gene location (Mouse) Chr. Chromosome 17 (mouse) Band 17|17 E1.3- E2 Start 73,414,980 bp End 73,550,363 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in myocardium of left ventricle pancreatic epithelial cell mucosa of ileum pancreatic ductal cell endothelial cell testicle jejunal mucosa saphenous vein right ventricle bronchial epithelial cell Top expressed in epithelium of small intestine right ventricle Ileal epithelium saccule myocardium of ventricle cardiac muscle tissue of left ventricle interventricular septum otic placode calvaria otic vesicle More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity acyltransferase activity protein binding O-acyltransferase activity 1-acylglycerol-3-phosphate O-acyltransferase activity Cellular component integral component of membrane endoplasmic reticulum membrane membrane endoplasmic reticulum cytosol Biological process phosphatidic acid biosynthetic process multicellular organism development CDP-diacylglycerol biosynthetic process metabolism cardiolipin acyl-chain remodeling lipid metabolism phospholipid biosynthetic process phospholipid metabolic process phosphatidylinositol acyl-chain remodeling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 253558 225010 Ensembl ENSG00000172954 ENSMUSG00000054469 UniProt Q6UWP7 Q3UN02 RefSeq (mRNA) NM_001002257 NM_001304445 NM_001304446 NM_182551 NM_001081071 NM_001177967 NM_001177968 RefSeq (protein) NP_001002257 NP_001291374 NP_001291375 NP_872357 NP_001074540 NP_001171438 NP_001171439 Location (UCSC) Chr 2: 30.45 – 30.64 Mb Chr 17: 73.41 – 73.55 Mb PubMed search
Wikidata
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Lysocardiolipin acyltransferase 1 is a protein that in humans is encoded by the LCLAT1 gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000172954 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000054469 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Lysocardiolipin acyltransferase 1". Retrieved 2018-01-18.

Further reading

• Zhao Y, Chen YQ, Li S, Konrad RJ, Cao G (2009). "The microsomal cardiolipin remodeling enzyme acyl-CoA lysocardiolipin acyltransferase is an acyltransferase of multiple anionic lysophospholipids". J. Lipid Res. 50 (5): 945–56. doi:10.1194/jlr.M800567-JLR200. PMC 2666181. PMID 19075029.

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