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MIB2 (gene)

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Protein-coding gene in the species Homo sapiens
MIB2
Identifiers
AliasesMIB2, ZZANK1, ZZZ5, mindbomb E3 ubiquitin protein ligase 2, MIB E3 ubiquitin protein ligase 2
External IDsOMIM: 611141; MGI: 2679684; HomoloGene: 16062; GeneCards: MIB2; OMA:MIB2 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)
Chromosome 1 (human)Genomic location for MIB2Genomic location for MIB2
Band1p36.33Start1,615,454 bp
End1,630,605 bp
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)
Chromosome 4 (mouse)Genomic location for MIB2Genomic location for MIB2
Band4|4 E2Start155,739,134 bp
End155,753,655 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • granulocyte

  • apex of heart

  • anterior pituitary

  • right ovary

  • left ovary

  • right hemisphere of cerebellum

  • right uterine tube

  • muscle of thigh

  • left uterine tube

  • skin of abdomen
Top expressed in
  • granulocyte

  • primary visual cortex

  • superior frontal gyrus

  • internal carotid artery

  • external carotid artery

  • cerebellar cortex

  • dentate gyrus of hippocampal formation granule cell

  • subiculum

  • Rostral migratory stream

  • neural layer of retina
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

142678

76580

Ensembl

ENSG00000197530

ENSMUSG00000029060

UniProt

Q96AX9

Q8R516

RefSeq (mRNA)

NM_001170686
NM_001170687
NM_001170688
NM_001170689
NM_080875

NM_001256107
NM_001256108
NM_001256110
NM_145124
NM_001369161

NM_001369162
NM_001369163
NM_001369164
NM_001369165
NM_001369166
NM_001369167
NM_001369168

RefSeq (protein)

NP_001164157
NP_001164158
NP_001164159
NP_001164160
NP_543151

NP_001243036
NP_001243037
NP_660106
NP_001356090
NP_001356091

NP_001356092
NP_001356093
NP_001356094
NP_001356095
NP_001356096
NP_001356097

Location (UCSC)Chr 1: 1.62 – 1.63 MbChr 4: 155.74 – 155.75 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

E3 ubiquitin-protein ligase MIB2 is an enzyme that in humans is encoded by the MIB2 gene.


Interactions

MIB2 (gene) has been shown to interact with Actin, alpha 1.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000197530Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000029060Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y, Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H, Sugano S (May 2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways". Oncogene. 22 (21): 3307–18. doi:10.1038/sj.onc.1206406. PMID 12761501. S2CID 38880905.
  6. "Entrez Gene: MIB2 mindbomb homolog 2 (Drosophila)".
  7. Takeuchi T, Heng Henry H Q, Ye Christine J, Liang Sheng-Ben, Iwata Jun, Sonobe Hiroshi, Ohtsuki Yuji (Oct 2003). "Down-regulation of a novel actin-binding molecule, skeletrophin, in malignant melanoma". Am. J. Pathol. 163 (4). United States: 1395–404. doi:10.1016/S0002-9440(10)63497-9. ISSN 0002-9440. PMC 1868282. PMID 14507647.

Further reading


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