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| Names | |
|---|---|
| Preferred IUPAC name 2-Hydroxy-3-(morpholin-4-yl)propane-1-sulfonic acid | |
| Other names MOPSO, 3-morpholino-2-hydroxypropanesulfonic acid, 3-morpholino-2HOPSA | |
| Identifiers | |
| CAS Number | |
| 3D model (JSmol) | |
| ECHA InfoCard | 100.063.607 
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| EC Number |
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| PubChem CID | |
| UNII | |
| CompTox Dashboard (EPA) | |
InChI
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SMILES
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| Properties | |
| Chemical formula | C7H15NO5S |
| Molar mass | 225.259 g/mol |
| Appearance | White crystalline powder |
| Melting point | 270–290 °C (518–554 °F; 543–563 K) |
| Acidity (pKa) | 6.9 |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
| Main hazards | Irritant |
| GHS labelling: | |
| Signal word | Warning |
| Hazard statements | H315, H319, H335 |
| Precautionary statements | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501 |
| Flash point | Non-flammable |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references | |
MOPSO is a zwitterionic organic chemical buffering agent; one of Good's buffers. MOPSO and MOPS (3-morpholinopropanesulfonic acid) are chemically similar, differing only in the presence of a hydroxyl group on the C-2 of the propane moiety. It has a useful pH range of 6.5-7.9 in the physiological range, making it useful for cell culture work. It has a pKa of 6.9 with ΔpKa/°C of -0.015 and a solubility in water at 0°C of 0.75 M.
MOPSO has been used as a buffer component for:
- Copper analysis via:
- Flow injection micellar technique of the catalytic reaction of 3-methyl-2-benzothiazolinone hydrazone and N-ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethoxyaniline
- Electrospray ionization quadrupole time-of-flight mass spectroscopy to measure MOPSO-copper chelated complexes
- Discontinuous gel electrophoresis on rehydratable polyacrylamide gels
- Buffered charcoal yeast extract agar
- Fixing cells in urine in a buffered alcohol
- Testing crude oil bioremediation products in marine environments
See also
References
- "Compound Summary for CID 109333". PubChem. 2005-03-27.
- "MOPSO". Sigma-Aldrich.
- "Biological Buffers". Sigma-Aldrich.
- "MOPSO sodium salt" (PDF). Sigma-Aldrich.