MPB can refer to:
Biology
- Mountain pine beetle, a barkbeetle in the US and Canada
Health and science
- Male pattern baldness
- Morphotropic phase boundary, a zone e.g. in PZT ceramics
Companies and agencies
- Mississippi Public Broadcasting, US
- Maritime and Port Bureau, Taiwan
- MP Birla Group, India
Arts and culture
- Monthly Playboy, Japanese edition
- Música popular brasileira, Brazilian popular music
- MPB4, a Brazilian musical group
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