Mark Griffin may refer to:
Musicians
- Mark Griffin, American rapper and musician known professionally as MC 900 Ft. Jesus
- Marc Griffin, American rapper and musician known professionally as Marc E. Bassy
Others
- Mark Griffin (entrepreneur), billiards promoter and owner of CueSports International
- Mark Griffin (politician) (born 1985), Scottish politician
- Mark Griffin (spiritual teacher) (born 1954), American spiritual teacher
- Mark Griffin (actor) (born 1968), British actor
- Mark Griffin (rugby union) (born 1975), rugby union player
- Marc Griffin (judge) (born 1956), American lawyer
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