Mattila is a Finnish surname. Notable people with the surname include:
- Hanna-Leena Mattila (born 1968), Finnish politician
- Jaakko Mattila (born 1976), Finnish painter
- Jarno Mattila (born 1984), Finnish footballer
- Karita Mattila (born 1960), opera soprano
- Olavi J. Mattila (1918–2013), Finnish Trade and Industry Ministry official
- Pertti Mattila (born 1948), Finnish mathematician
- Pirkko Mattila (born 1964), Finnish politician
- Risto Mattila (born 1981), Finnish snowboarder
- Sakari Mattila (born 1989), Finnish footballer
- Topi Mattila (born 1946), Finnish ski jumper
- Ville Mattila (1903–1987), Finnish cross country skier
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