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Melarsomine

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Chemical compound Pharmaceutical compound
Melarsomine
Skeletal formula of melarsomine
Space-filling model of the melarsomine molecule
Clinical data
Trade namesImmiticide, Diroban
AHFS/Drugs.comInternational Drug Names
ATC code
  • none
Identifiers
IUPAC name
  • Bis(2-aminoethyl) {4-phenyl}arsonodithioite
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC13H21AsN8S2
Molar mass428.41 g·mol
3D model (JSmol)
SMILES
  • C1=CC(=CC=C1NC2=NC(=NC(=N2)N)N)(SCCN)SCCN
InChI
  • InChI=1S/C13H21AsN8S2/c15-5-7-23-14(24-8-6-16)9-1-3-10(4-2-9)19-13-21-11(17)20-12(18)22-13/h1-4H,5-8,15-16H2,(H5,17,18,19,20,21,22)
  • Key:MGEOLZFMLHYCFZ-UHFFFAOYSA-N
  (verify)

Melarsomine (melaminylthioarsenate) is an arsenic-based anthelmintic. In the U.S., it is marketed under the trade names Immiticide (Merial) and Diroban (Zoetis), and is approved by the FDA's Center for Veterinary Medicine for the treatment of adult heartworm (Dirofilaria immitis) infection in dogs. It is not approved for treatment in cats, or dogs in late-stage infection.

References

  1. Tilley LP (2008). Manual of Canine and Feline Cardiology. Elsevier Health Sciences. pp. 194–197. ISBN 978-1-4160-2398-2.
  2. Bonagura JD, Twedt DC (2013). Kirk's Current Veterinary Therapy XV. Elsevier Health Sciences. p. 2502. ISBN 978-0-323-22762-9.

External links


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