Mengel is a surname. Notable people with the surname include:
- Alex Mengel (1950–1985), Guyanese-born suspected serial killer
- Charles Mengel (born 1933), Australian cricketer
- Christian Gotlob Mengel (1716–1769), Danish publisher, translator and bookseller
- Ernest Mengel (1913–1968), Luxembourgian footballer
- Friederike Mengel (born 1979), German economist
- Georg Mengel (1612–1667), German composer
- Hans Mengel (1917–1943), German footballer
- Levi Walter Mengel (1868–1941), American entomologist
- Tanner Austin Mengel (born 1997), American physicist
See also
- Northern Territory v Mengel, an Australian court case
- Mengele (disambiguation)
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