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Mesopotamia is the historical region between the Tigris and Euphrates rivers, largely corresponding with the territory of modern Iraq.

Mesopotamia may also refer to:

Places

Middle East

• Geographically, the Tigris–Euphrates river system
  • Upper Mesopotamia
  • Lower Mesopotamia
• Mesopotamia (Roman province), a Roman province extant in the 2nd through 7th centuries
• Mesopotamia (theme), a Byzantine province extant in the 10th and 11th centuries
• Mandatory Mesopotamia, the geopolitical entity created in Mesopotamia (Iraq) under British administration in 1920–1921

Other locations

• Mesopotamia, Argentina, the name of the northeast region of Argentina located between the rivers Paraná and Uruguay
• Mesopotamia, Antioquia, a district in La Unión municipality in Antioquia Department, Colombia.
• Mesopotamia Township, Trumbull County, Ohio, United States
• Mesopotam, a village in Albania
• Mesopotamia, Kastoria, a former municipality in Greece
• Mesopotamia, New Zealand, an area at the head of the Rangitata River
  • Mesopotamia Station, a historic high country farm at Mesopotamia, New Zealand
• Mesopotamia, Oxford, the name of land between two rivers in the Oxford University Parks, England
• Mesopotamia, Saint Vincent and the Grenadines, a village in Saint Vincent and the Grenadines
• Mesopotamia (Belize House constituency), a Belize City-based electoral constituency

In popular culture

• Mesopotamia (EP), an EP by The B-52's; or the title track of that album
• "Mesopotamia", the first track from the album Cruel Melody by Black Light Burns
• "The Mesopotamians", the last track in the album The Else by They Might Be Giants
• "Mesopotamia", the book by Serhii Zhadan

Other uses

• Mesopotamian crow, a bird native to the region of Mesopotamia
• "Mesopotamia", the Japanese name for the 1991 video game Somer Assault

• Disambiguation pages
• Place name disambiguation pages