Metallocarboxypeptidase D - Misplaced Pages

Metallocarboxypeptidase D (EC 3.4.17.22, carboxypeptidase D (cattle, human, mouse, rat), gp180 (duck)) is an enzyme. This enzyme catalyses the following chemical reaction

Releases C-terminal Arg and Lys from polypeptides

This enzyme is activated by Co, and inhibited by guanidinoethylmercaptosuccinic acid.

References

Kuroki K, Eng F, Ishikawa T, Turck C, Harada F, Ganem D (June 1995). "gp180, a host cell glycoprotein that binds duck hepatitis B virus particles, is encoded by a member of the carboxypeptidase gene family". The Journal of Biological Chemistry. 270 (25): 15022–8. doi:10.1074/jbc.270.25.15022. PMID 7797483.
Song L, Fricker LD (October 1995). "Purification and characterization of carboxypeptidase D, a novel carboxypeptidase E-like enzyme, from bovine pituitary". The Journal of Biological Chemistry. 270 (42): 25007–13. doi:10.1074/jbc.270.42.25007. PMID 7559630.
Song L, Fricker LD (November 1996). "Tissue distribution and characterization of soluble and membrane-bound forms of metallocarboxypeptidase D". The Journal of Biological Chemistry. 271 (46): 28884–9. doi:10.1074/jbc.271.46.28884. PMID 8910535.

External links

Metallocarboxypeptidase+D at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Hydrolase: proteases (EC 3.4)

3.4.11-19: Exopeptidase

3.4.11	Aminopeptidase Alanine Arginyl Aspartyl Cystinyl Leucyl Glutamyl Methionyl 1 2 O
3.4.13	Dipeptidase 1 2 3
3.4.14	Dipeptidyl peptidase Cathepsin C Dipeptidyl peptidase-4 Tripeptidyl peptidase Tripeptidyl peptidase I Tripeptidyl peptidase II
3.4.15	Angiotensin-converting enzyme
3.4.16	Serine type carboxypeptidases: Cathepsin A DD-Transpeptidase
3.4.17	Metalloexopeptidases Carboxypeptidase A A2 B C E Glutamate II
Other/ungrouped	Metalloexopeptidase

3.4.21-25: Endopeptidase

Other/ungrouped: Amyloid precursor protein secretase

3.4.99: Unknown

Staphylokinase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

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Biology

Category:

EC 3.4.17