Michael or Mike Fleming may refer to:
- Sir Michael le Fleming, 4th Baronet (1748–1806), member of parliament for Westmorland
- Michael Anthony Fleming (1792–1850), bishop of Newfoundland
- Michael P. Fleming (born 1963), Texas-based lawyer
- Michael Fleming (historian), professor of history at the Polish University Abroad in London
- Mike Fleming (talk radio host), American conservative radio talk show host
- Mike Fleming (footballer), English footballer
- Mick Fleming, Irish Gaelic footballer
- Michael Fleming (MP) (1668–1718), member of parliament for Westmorland, 1707–1708
- Michael Fleming (musician) [de] (born 1935), American jazz bassist; see I Talk with the Spirits
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