Micheletti is an Italian surname, derived from the given name Michele. Notable people with the surname include:
- Andrea Micheletti (born 1991), Italian rower
- Estadio Humberto Micheletti
- Joe Micheletti, hockey analyst
- Luisa Micheletti, Brazilian presenter
- Pat Micheletti, American hockey player
- Pietro Micheletti
- Roberto Micheletti, de facto President of Honduras for seven months in 2009–2010, following the 2009 Honduran coup d'etat
- J. Morgan Micheletti, American ophthalmologist
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