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Microvenular hemangioma

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Medical condition
Microvenular hemangioma
Other namesMicrocapillary hemangioma
SpecialtyOncology Edit this on Wikidata

Microvenular hemangioma is an acquired benign vascular tumor that presents as an asymptomatic, slowly growing, 0.5- to 2.0 cm reddish lesion on the forearms or other sites of young to middle-aged adults. The cause of microvenular hemangioma is unknown, however it has been associated with immunosuppression.

Signs and symptoms

Microvenular hemangioma appears as slow-growing, frequently numerous lesions, erythematous, violaceous, or moderately pruriginous macules, papules, or nodules without any symptoms. They usually appear on the forearm. There have also been reports of lesions on the soles of the feet, forehead, legs, and chest.

Causes

Although the exact cause of microvenular hemangioma is uncertain, it has been found in certain instances during pregnancy or after changes in hormonal contraception. In certain circumstances, imbalanced sex hormones could potentially be the cause. Microvenular hemangioma has also been associated with immunosuppression.

Diagnosis

Multiple distinct red globules are seen under a microscope, and a finely pigmented network is seen around the periphery. Histologically, microvenular hemangioma is made up of venules with thin walls that branch erratically and have barely noticeable vascular lumina. The dermis's collagen bundles are thickened. Pericytes envelop the endothelial cells, which can exhibit a combination of plump and flat cells without pleomorphism or mitotic patterns.

Immunohistochemically, an microvenular hemangioma's endothelial cells show positive staining for CD31, CD34, and factor VIII, while its pericytes show positive staining for SMA. However, neither cell shows positive staining for podoplanin.

The differential diagnosis for microvenular hemangioma includes acquired (tufted) angioma, Kaposi sarcoma, Kaposiform hemangioendothelioma, and sclerosing hemangioma.

Treatment

The treatment for microvenular hemangioma is surgical excision.

See also

References

  1. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. p. 596. ISBN 978-0-7216-2921-6.
  3. Xu, Xiu-Lian; Xu, Cui-Rong; Chen, Hao; Cao, Yuan-Hua; Zeng, Xue-Si; Sun, Jian-Fang; Guo, Ying (2010). "Eruptive Microvenular Hemangiomas in 4 Chinese Patients: Clinicopathologic Correlation and Review of the Literature". The American Journal of Dermatopathology. 32 (8): 837–840. doi:10.1097/DAD.0b013e3181d74290. ISSN 0193-1091. PMID 20881833.
  4. Giacaman, A.; del Pozo, L.J.; Bauzá, A.; Saus, C. (2018). "Microvenular Hemangioma: Morphological Study of 3 Cases". Actas Dermo-Sifiliográficas (English Edition). 109 (4). Elsevier BV: 381–384. doi:10.1016/j.adengl.2017.06.022. ISSN 1578-2190.
  5. Bantel, E.; Grosshans, E.; Ortonne, J. P. (1989-12-15). "". Zeitschrift für Hautkrankheiten. 64 (12): 1071–1074. ISSN 0301-0481. PMID 2534452.
  6. ^ Ai, Dong Fang; Li, Yan; Jindal, Aikaj; Li, Ping (2014). "Multiple microvenular hemangioma: A case report". Oncology Letters. 7 (1): 275–277. doi:10.3892/ol.2013.1659. ISSN 1792-1074. PMC 3861598. PMID 24348863.
  7. Tur-González, Raquel; González-de Arriba, Ana; Martín-López, María Rocío; Ramos-Nieto, María Luz (2015). "Hemangioma microvenular: lesión vascular benigna de patrón infiltrante. Presentación de 3 casos y revisión de la literatura". Revista Española de Patología (in Spanish). 48 (4). Elsevier BV: 203–207. doi:10.1016/j.patol.2015.07.004. ISSN 1699-8855.
  8. ^ Scalvenzi, Massimiliano; De Natale, Flora; Francia, Maria Grazia; Balato, Anna (2007). "Dermoscopy of Microvenular Hemangioma: Report of a Case". Dermatology. 215 (1). S. Karger AG: 69–71. doi:10.1159/000102038. ISSN 1018-8665. PMID 17587844.
  9. Aloi, Filippo; Tomasini, Carlo; Pippione, Mario (1993). "Microvenular Hemangioma". The American Journal of Dermatopathology. 15 (6). Ovid Technologies (Wolters Kluwer Health): 534–538. doi:10.1097/00000372-199312000-00003. ISSN 0193-1091.
  10. Fukunaga, Masaharu; Ushigome, Shinichiro (1998). "Microvenular hemangioma". Pathology International. 48 (3). Wiley: 237–239. doi:10.1111/j.1440-1827.1998.tb03899.x. ISSN 1320-5463.
  11. Stefanaki, Christina; Stefanaki, Kalliopi; Floros, Konstantinos; Rontogiani, Dimitra; Georgala, Sofia (2005). "Microvenular Hemangioma: A Rare Vascular Lesion". The Journal of Dermatology. 32 (5). Wiley: 402–404. doi:10.1111/j.1346-8138.2005.tb00915.x. ISSN 0385-2407. PMID 16043906.
  12. Fernandez-Flores, Angel (2008). "Lack of expression of podoplanin by microvenular hemangioma". Pathology - Research and Practice. 204 (11). Elsevier BV: 817–821. doi:10.1016/j.prp.2008.06.002. ISSN 0344-0338. PMID 18650031.
  13. ^ Mocellin, Simone (2021). "Microvenular Hemangioma". Soft Tissue Tumors. Cham: Springer International Publishing. pp. 553–554. doi:10.1007/978-3-030-58710-9_173. ISBN 978-3-030-58709-3.

Further reading

External links

ClassificationD
External resources
Tumours of blood vessels
Blood vessel
Lymphatic
Either
Category: