Millington is a surname. Notable people with the surname include:
- Abel Millington (1787–1838), American politician
- Charles S. Millington (1855–1913), American politician and banker from New York
- Charlie Millington (1882–1945), English footballer
- Ernest Millington (1916–2009), British politician
- Grenville Millington (born 1951), Chester City footballer
- Gordon Millington (1848–1923), New Zealand cricketer
- James Heath Millington (1799–1872), British painter
- June Millington (born 1948), Filipino-American guitarist, songwriter, producer, educator, and actress
- Lucy Millington (1825–1900), American botanist
- Margaret Millington (1944–1973), English-born mathematician
- Mary Millington (1945–1979), British porn star
- Mil Millington, British author
- Richard Millington, British ornithologist
- Ross Millington (born 1989), British long-distance runner
- Sir Thomas Millington (1628–1704), English physician
- Tony Millington (1943–2015), Welsh footballer
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