Mizukami may refer to:
- Mizukami, Kumamoto, a village in Kuma District, Kumamoto Prefecture, Japan
- Mizukami Dam, a dam in Nagano Prefecture, Japan
Notable people with the surname
- Noriyasu Mizukami (水上 則安, born 1947), Japanese long-distance runner
- Satoshi Mizukami (水上 悟志, born 1980), Japanese manga artist
- Koshi Mizukami (水上恒司, born 1999), Japanese actor
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