Mstislav Rostislavich may refer to:
- Mstislav Rostislavich of Smolensk (died 1180), nicknamed "the Brave" (Russian: Храбрый; Ukrainian: Хоро́брий), Prince of Smolensk (r. 1175–1177) and Prince of Novgorod (r. 1179–1180).
- Mstislav Rostislavich of Rostov (died 1178), nicknamed "the Eyeless" (Russian/Ukrainian: Безокий) due to being blinded by his step-uncle Vsevolod the Big Nest during the 1174–1177 Suzdalian war of succession.
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