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Mucinous nevus

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Medical condition
Mucinous nevus
Other namesNevus mucinosus
SpecialtyDermatology

Mucinous nevus is a rare cutaneous condition characterized by hamartoma that can be congenital or acquired. Mucinous nevus presents as multiple skin-coloured or brown asymptomatic papules or plaques. Mucinous nevus is diagnosed based of histological features. Treatment is not needed.

Signs and symptoms

Mucinous nevus appears as several skin-coloured to brownish papules or plaques that are asymptomatic; the individual lesions merge and expand to form a unilateral or zosteriform feature that is verrucous or nevoid. It normally starts to develop in early adulthood or from birth. The main location is the trunk, which includes the back.

Causes

There has been reports of familial mucinous nevus, however there have been no reports of genetic abnormalities.

Diagnosis

Histologically, diffuse band-like mucin deposits in the uppermost layer of the dermis are indicative of mucinous nevus. Hyaluronic acid is assumed to be the component of mucin since it reacts positively with alcian blue at pH 2.5 but does not at pH 0.5.

Treatment

Mucinous nevi are benign and don't need to be treated other than for aesthetic reasons. Carbon dioxide laser therapy, scalpel dermabrasion, and surgical excision are treatment options.

See also

References

  1. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. ^ Cobos, Gabriela; Braunstein, Inbal; Abuabara, Katrina; Chu, Emily Y.; James, William (2014-09-01). "Mucinous Nevus: Report of a Case and Review of the Literature". JAMA Dermatology. 150 (9): 1018. doi:10.1001/jamadermatol.2013.9451. ISSN 2168-6068. PMID 25029469.
  3. Tardío, Juan C.; Granados, Rosario (2010-07-08). "The cellular component of the mucinous nevus consists of CD34-positive fibroblasts". Journal of Cutaneous Pathology. 37 (9). Wiley: 1019–1020. doi:10.1111/j.1600-0560.2009.01426.x. ISSN 0303-6987. PMID 19765172.
  4. ^ CHEN, CHIA-WEI; TSAI, TSEN-FANG; CHEN, YU-FU; HUNG, CHIH-MING (2008). "Familial Mucinous Nevus". Pediatric Dermatology. 25 (2). Wiley: 288–289. doi:10.1111/j.1525-1470.2008.00664.x. ISSN 0736-8046. PMID 18429813.
  5. ^ Perez-Crespo, M; Lopez-Navarro, N; Betlloch, I; Herrera, E; Niveiro, M; Gallego, E (2011-09-25). "Acquired and familial mucinous nevus". International Journal of Dermatology. 50 (10). Wiley: 1283–1285. doi:10.1111/j.1365-4632.2010.04520.x. ISSN 0011-9059. PMID 21950298.
  6. Lee, Min Young; Byun, Ji Yeon; Choi, Hae Young; Choi, You Won (2018). "Mucinous Nevus". Annals of Dermatology. 30 (4). Korean Dermatological Association and The Korean Society for Investigative Dermatology: 465–467. doi:10.5021/ad.2018.30.4.465. ISSN 1013-9087. PMC 6029955. PMID 30065589.
  7. Lim, J-H.; Cho, S-H.; Kim, H-O.; Kim, C-W.; Park, Y-M. (2003). "Mucinous naevus with atypical features". British Journal of Dermatology. 148 (5). Oxford University Press (OUP): 1064–1066. doi:10.1046/j.1365-2133.2003.05334.x. ISSN 0007-0963. PMID 12786849.
  8. BRAKMAN, M.; STARINK, TH.M.; TAFELKRUYER, J.; BOS, J.D. (1994). "Linear connective tissue naevus of the proteoglycan type ('naevus mucinosus')". British Journal of Dermatology. 131 (3). Oxford University Press (OUP): 368–370. doi:10.1111/j.1365-2133.1994.tb08526.x. ISSN 0007-0963.
  9. Chi, Ching-Chi; Wang, Shu-Hui; Lin, Paul Y. (2009). "Combined epidermal-connective tissue nevus of proteoglycan (a type of mucinous nevus): a case report and literature review". Journal of Cutaneous Pathology. 36 (7). Wiley: 808–811. doi:10.1111/j.1600-0560.2008.01123.x. ISSN 0303-6987. PMID 19519615.

Further reading

External links

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