Murugaiyan may refer to:
- Anucharan Murugaiyan, Indian director
- K. Murugaiyan, Indian communist politician
- P. Murugaiyan, Indian politician and former Member of the Legislative Assembly of Tamil Nadu
- S. Murugaiyan, Indian politician and former Member of the Legislative Assembly of Tamil Nadu
- S.G. Murugaiyan, Indian communist politician in Tamil Nadu
- Thavil Kongampattu A V Murugaiyan (born 1964), Indian classical musician
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