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MYBL1
Identifiers
Aliases	MYBL1, A-MYB, AMYB, MYB proto-oncogene like 1
External IDs	OMIM: 159405; MGI: 99925; HomoloGene: 32045; GeneCards: MYBL1; OMA:MYBL1 - orthologs
Gene location (Human) Chr. Chromosome 8 (human) Band 8q13.1 Start 66,562,175 bp End 66,614,247 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1 A2|1 2.08 cM Start 9,737,640 bp End 9,770,434 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon vena cava sperm body of tongue Skeletal muscle tissue of rectus abdominis Pons granulocyte parotid gland pericardium superior surface of tongue Top expressed in spermatocyte spermatid zygote secondary oocyte tail of embryo genital tubercle female urethra ventricular zone primary oocyte renal corpuscle More reference expression data BioGPS n/a
Gene ontology Molecular function RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus Biological process positive regulation of transcription, DNA-templated regulation of transcription, DNA-templated transcription, DNA-templated positive regulation of transcription by RNA polymerase II transcription by RNA polymerase II mitotic cell cycle male meiosis I spermatogenesis negative regulation of transposition cell differentiation piRNA biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4603 17864 Ensembl ENSG00000185697 ENSMUSG00000025912 UniProt P10243 P51960 RefSeq (mRNA) NM_001080416 NM_001144755 NM_001294282 NM_001290397 NM_008651 RefSeq (protein) NP_001073885 NP_001138227 NP_001281211 NP_001277326 NP_032677 Location (UCSC) Chr 8: 66.56 – 66.61 Mb Chr 1: 9.74 – 9.77 Mb PubMed search
Wikidata
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MYB proto-oncogene like 1 is a protein that in humans is encoded by the MYBL1 gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000185697 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000025912 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: MYB proto-oncogene like 1". Retrieved 2016-11-15.

Further reading

• Ramkissoon LA, Horowitz PM, Craig JM, Ramkissoon SH, Rich BE, Schumacher SE, McKenna A, Lawrence MS, Bergthold G, Brastianos PK, Tabak B, Ducar MD, Van Hummelen P, MacConaill LE, Pouissant-Young T, Cho YJ, Taha H, Mahmoud M, Bowers DC, Margraf L, Tabori U, Hawkins C, Packer RJ, Hill DA, Pomeroy SL, Eberhart CG, Dunn IF, Goumnerova L, Getz G, Chan JA, Santagata S, Hahn WC, Stiles CD, Ligon AH, Kieran MW, Beroukhim R, Ligon KL (2013). "Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1". Proc. Natl. Acad. Sci. U.S.A. 110 (20): 8188–93. Bibcode:2013PNAS..110.8188R. doi:10.1073/pnas.1300252110. PMC 3657784. PMID 23633565.

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