NG2 (or Ng2) may refer to:
- Neuron-glial antigen 2, a chondroitin sulfate proteoglycan that in humans is encoded by the CSPG4 gene
- Ninja Gaiden II, a 2008 video game
- Ng2 business park, a business park in the city of Nottingham, England
- NG2 tram stop, a tram stop in the city of Nottingham, England
- NG (duo), a Puerto Rican Salsa duo
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