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NOP58
Identifiers
Aliases	NOP58, NOP5, NOP5/HSPC120, NOP58 ribonucleoprotein
External IDs	OMIM: 616742; MGI: 1933184; HomoloGene: 7024; GeneCards: NOP58; OMA:NOP58 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2q33.1 Start 202,265,736 bp End 202,303,661 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1|1 C2 Start 59,724,130 bp End 59,758,203 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic epithelial cell pancreatic ductal cell gingival epithelium sural nerve mucosa of sigmoid colon body of pancreas Achilles tendon tonsil left ovary anterior pituitary Top expressed in tail of embryo epiblast genital tubercle ventricular zone blastocyst yolk sac embryo embryo morula morula More reference expression data BioGPS n/a
Gene ontology Molecular function ATPase binding protein binding TFIID-class transcription factor complex binding snoRNA binding RNA binding Cellular component small-subunit processome Cajal body pre-snoRNP complex membrane nucleoplasm nucleolus nucleus box C/D RNP complex sno(s)RNA-containing ribonucleoprotein complex fibrillar center cytosol Biological process ribosome biogenesis snoRNA localization cell growth rRNA processing rRNA modification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51602 55989 Ensembl ENSG00000055044 ENSMUSG00000026020 UniProt Q9Y2X3 Q6DFW4 RefSeq (mRNA) NM_015934 NM_018868 RefSeq (protein) NP_057018 NP_061356 Location (UCSC) Chr 2: 202.27 – 202.3 Mb Chr 1: 59.72 – 59.76 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Nucleolar protein 58 is a protein that in humans is encoded by the NOP58 gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000055044 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000026020 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Lyman SK, Gerace L, Baserga SJ (Jan 2000). "Human Nop5/Nop58 is a component common to the box C/D small nucleolar ribonucleoproteins". RNA. 5 (12): 1597–604. doi:10.1017/S1355838299991288. PMC 1369881. PMID 10606270.
6. Nelson SA, Santora KE, LaRochelle WJ (Sep 2000). "Isolation and characterization of a novel PDGF-induced human gene". Gene. 253 (1): 87–93. doi:10.1016/S0378-1119(00)00232-8. PMID 10925205.
7. "Entrez Gene: NOP5/NOP58 nucleolar protein NOP5/NOP58".

Further reading

• Pintard L, Kressler D, Lapeyre B (2000). "Spb1p Is a Yeast Nucleolar Protein Associated with Nop1p and Nop58p That Is Able To Bind S-Adenosyl-l-Methionine In Vitro". Mol. Cell. Biol. 20 (4): 1370–81. doi:10.1128/MCB.20.4.1370-1381.2000. PMC 85287. PMID 10648622.
• Yang Y, Isaac C, Wang C, et al. (2000). "Conserved Composition of Mammalian Box H/ACA and Box C/D Small Nucleolar Ribonucleoprotein Particles and Their Interaction with the Common Factor Nopp140". Mol. Biol. Cell. 11 (2): 567–77. doi:10.1091/mbc.11.2.567. PMC 14794. PMID 10679015.
• Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
• Verheggen C, Lafontaine DL, Samarsky D, et al. (2002). "Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments". EMBO J. 21 (11): 2736–45. doi:10.1093/emboj/21.11.2736. PMC 126019. PMID 12032086.
• Watkins NJ, Dickmanns A, Lührmann R (2003). "Conserved Stem II of the Box C/D Motif Is Essential for Nucleolar Localization and Is Required, Along with the 15.5K Protein, for the Hierarchical Assembly of the Box C/D snoRNP". Mol. Cell. Biol. 22 (23): 8342–52. doi:10.1128/MCB.22.23.8342-8352.2002. PMC 134055. PMID 12417735.
• Scherl A, Couté Y, Déon C, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Watkins NJ, Lemm I, Ingelfinger D, et al. (2005). "Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex". Mol. Cell. 16 (5): 789–98. doi:10.1016/j.molcel.2004.11.012. hdl:11858/00-001M-0000-0012-EB89-8. PMID 15574333.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

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