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New methylene blue

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A substance used as a blue dye or stain and as a medication
New methylene blue
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.026.833 Edit this at Wikidata
PubChem CID
UNII
InChI
  • InChI=1S/C18H22N3S.ClH/c1-5-19-13-9-17-15(7-11(13)3)21-16-8-12(4)14(20-6-2)10-18(16)22-17;/h7-10,19-20H,5-6H2,1-4H3;1H/q+1;/p-1Key: NZYCYASKVWSANA-UHFFFAOYSA-M
  • InChI=1/C18H22N3S.ClH/c1-5-19-13-9-17-15(7-11(13)3)21-16-8-12(4)14(20-6-2)10-18(16)22-17;/h7-10,19-20H,5-6H2,1-4H3;1H/q+1;/p-1Key: NZYCYASKVWSANA-REWHXWOFAR
SMILES
  • .Cc1cc2nc3cc(C)c(cc3c2cc1NCC)NCC
Properties
Chemical formula C18H22N3S:SCl ZnCl2
Molar mass 484.22 g/mol
Melting point 239 °C (462 °F; 512 K)
Boiling point Decomposes
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒N verify (what is  ?) Infobox references
Chemical compound

New methylene blue (also NMB) is an organic compound of the thiazine class of heterocycles. It is used as a stain and as an antimicrobial agent. It is classified as an azine dye, and the chromophore is a cation, the anion is often unspecified.

Applications

NMB is a staining agent used in diagnostic cytopathology and histopathology, typically for staining immature red blood cells. It is a supravital stain. It is closely related to methylene blue, an older stain in wide use.

Safety

New methylene blue is toxic. Skin contact or inhalation should be avoided.

See also

References

  1. Vennerstrom, Jonathan L.; Makler, Michael T.; Angerhofer, Cidy K.; Williams, Jean A. "Antimalarial dyes revisited: xanthenes, azines, oxazines, and thiazine" Antimicrobial Agents and Chemotherapy (1995), 39(12), 2671–7. doi:10.1128/AAC.39.12.2671.
  2. "Reticulocyte Count" (PDF). Prentice-Hall.
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