Niche may refer to:
Science
- Developmental niche, a concept for understanding the cultural context of child development
- Ecological niche, a term describing the relational position of an organism's species
- Niche differentiation, in ecology, the process by which competing species use the environment differently in a way that helps them to coexist
- Niche (protein structural motif)
- Stem-cell niche, the necessary cellular environment of a stem cell
Business
- Niche market, a focused, targetable portion (subset) of a market sector
- Niche blogging, a blog focused on a niche market
Other uses
- Bassline (music genre), a type of music related to UK garage also called Niche
- Niche (architecture), an exedra or an apse that has been reduced in size
- A cell of a columbarium for a cremation urn
- Niche (company), an Internet search and review service
- Niche (horse), a British Thoroughbred racehorse
- Niche (video game), a 2017 video game
- Niche, a character in the manga Tegami Bachi
- Niche (footballer), Bissau-Guinean footballer
- Network in Canadian History and Environment, a group of Canadian environmental historians
- Nishe, a B-Side from the 2000 single Unintended by English rock band, Muse
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