Nyambe is both a masculine given name and a surname, especially used in Zambia. Notable people with the name include:
Surname
- Dora Moono Nyambe (1992–2024), Zambian humanitarian, educator, and TikToker
- Patrick Kakozi Nyambe (born 2002), Zambian sprinter
- Prisca Matimba Nyambe (born 1951), Zambian judge
- Ryan Nyambe (born 1997), Namibian footballer
Given name
- Nyambe Mulenga (born 1987), Zambian former footballer
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