OPI may refer to:
Organizations
- Order of Perpetual Indulgence or Sisters of Perpetual Indulgence
- The Office of Police Integrity, Victoria, Australia
Science and technology
Places
- Opi, Abruzzo, a comune in Italy
- Opi (archaeological site), Enugu State, Nigeria
Other uses
- Over the phone interpreting
- Oral Proficiency Interview
- OPI Products, a US nail polish manufacturer
- Opi, an Igbo musical instrument
- Oremus Pro Invicem, Latin for Let us Pray for each other (see List of Latin phrases (O))
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