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OSBPL9

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Protein-coding gene in the species Homo sapiens
OSBPL9
Identifiers
AliasesOSBPL9, ORP-9, ORP9, oxysterol binding protein like 9
External IDsOMIM: 606737; MGI: 1923784; HomoloGene: 69380; GeneCards: OSBPL9; OMA:OSBPL9 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)
Chromosome 1 (human)Genomic location for OSBPL9Genomic location for OSBPL9
Band1p32.3Start51,577,179 bp
End51,798,427 bp
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)
Chromosome 4 (mouse)Genomic location for OSBPL9Genomic location for OSBPL9
Band4|4 C7Start109,061,145 bp
End109,202,272 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • Achilles tendon

  • right lung

  • popliteal artery

  • tibial arteries

  • sural nerve

  • Epithelium of choroid plexus

  • renal medulla

  • retinal pigment epithelium

  • right coronary artery

  • gastric mucosa
Top expressed in
  • stroma of bone marrow

  • right kidney

  • granulocyte

  • proximal tubule

  • carotid body

  • iris

  • ankle

  • conjunctival fornix

  • vestibular membrane of cochlear duct

  • neural layer of retina
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

114883

100273

Ensembl

ENSG00000117859

ENSMUSG00000028559

UniProt

Q96SU4

A2A8Z1

RefSeq (mRNA)
NM_024586
NM_148904
NM_148905
NM_148906
NM_148907

NM_148908
NM_148909
NM_001330580
NM_001350208
NM_001350209
NM_001350210

NM_001134791
NM_133885
NM_173350
NM_001346502
NM_001355190

NM_001355191
NM_001368727

RefSeq (protein)
NP_001317509
NP_078862
NP_683702
NP_683703
NP_683704

NP_683705
NP_683706
NP_683707
NP_001337137
NP_001337138
NP_001337139

NP_001128263
NP_001333431
NP_598646
NP_775485
NP_001342119

NP_001342120
NP_001355656

Location (UCSC)Chr 1: 51.58 – 51.8 MbChr 4: 109.06 – 109.2 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Oxysterol binding protein-like 9 is a protein that in humans is encoded by the OSBPL9 gene.

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000117859Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000028559Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: oxysterol binding protein-like 9". Retrieved 2011-08-30.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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