Odetta Holmes (1930–2008) was an American singer, actress, guitarist, songwriter, and human rights activist.
Odetta may also refer to:
- Three albums by the singer:
- Odetta (1963 album), a compilation album
- Odetta (1967 album), a studio album
- Odetta (Silverwolf album) or To Ella, a 1998 live album
- Odetta (gastropod), a genus of sea snails
- Susannah Dean (also referred to as Odetta Holmes and Detta Walker), a fictional character from Stephen King's The Dark Tower series
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