Oley may refer to:
- People
- Barnabas Oley (1602–1686), English churchman and academic
- Johann Christoph Oley (1738–1789), German organist and composer
- Places
- Oley Valley, Pennsylvania
- Oley Township, Berks County, Pennsylvania
- Oley, Pennsylvania, a census-designated place within this township
- Other
- OleY, acronym for L-olivosyl-oleandolide 3-O-methyltransferase, an enzyme
- Oley, a car brand
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