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PCYOX1

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Protein-coding gene in the species Homo sapiens
PCYOX1
Identifiers
AliasesPCYOX1, PCL1, prenylcysteine oxidase 1
External IDsOMIM: 610995; MGI: 1914131; HomoloGene: 9458; GeneCards: PCYOX1; OMA:PCYOX1 - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)
Chromosome 2 (human)Genomic location for PCYOX1Genomic location for PCYOX1
Band2p13.3Start70,257,386 bp
End70,281,185 bp
Gene location (Mouse)
Chromosome 6 (mouse)
Chr.Chromosome 6 (mouse)
Chromosome 6 (mouse)Genomic location for PCYOX1Genomic location for PCYOX1
Band6|6 D1Start86,362,988 bp
End86,374,136 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • parotid gland

  • endothelial cell

  • parietal pleura

  • skin of hip

  • gingival epithelium

  • skin of thigh

  • Skeletal muscle tissue of biceps brachii

  • Skeletal muscle tissue of rectus abdominis

  • Brodmann area 23

  • visceral pleura
Top expressed in
  • urothelium

  • medullary collecting duct

  • transitional epithelium of urinary bladder

  • facial motor nucleus

  • cumulus cell

  • ureter

  • vestibular sensory epithelium

  • substantia nigra

  • Epithelium of choroid plexus

  • skin of external ear
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

51449

66881

Ensembl

ENSG00000116005

ENSMUSG00000029998

UniProt

Q9UHG3

Q9CQF9

RefSeq (mRNA)

NM_016297

NM_025823
NM_001355687

RefSeq (protein)

NP_057381

NP_080099
NP_001342616

Location (UCSC)Chr 2: 70.26 – 70.28 MbChr 6: 86.36 – 86.37 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Prenylcysteine oxidase 1 is an enzyme that in humans is encoded by the PCYOX1 gene.

See also

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000116005Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000029998Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Tschantz WR, Zhang L, Casey PJ (Jan 2000). "Cloning, expression, and cellular localization of a human prenylcysteine lyase". J Biol Chem. 274 (50): 35802–8. doi:10.1074/jbc.274.50.35802. PMID 10585463.
  6. Digits JA, Pyun HJ, Coates RM, Casey PJ (Oct 2002). "Stereospecificity and kinetic mechanism of human prenylcysteine lyase, an unusual thioether oxidase". J Biol Chem. 277 (43): 41086–93. doi:10.1074/jbc.M208069200. PMID 12186880.
  7. "Entrez Gene: PCYOX1 prenylcysteine oxidase 1".

Further reading


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