Misplaced Pages

POF1B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3BH9
Identifiers
Aliases	POF1B, POF, POF2B, premature ovarian failure, 1B, actin binding protein, POF1B actin binding protein
External IDs	OMIM: 300603; MGI: 1916943; HomoloGene: 11785; GeneCards: POF1B; OMA:POF1B - orthologs
Gene location (Human) Chr. X chromosome (human) Band Xq21.1 Start 85,277,396 bp End 85,379,717 bp
Gene location (Mouse) Chr. X chromosome (mouse) Band X|X E1 Start 111,548,128 bp End 111,608,348 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of arm skin of leg skin of abdomen rectum skin of thigh mucosa of sigmoid colon skin of hip jejunal mucosa gums mucosa of transverse colon Top expressed in skin of external ear skin of back epidermis hair follicle umbilical cord conjunctival fornix transitional epithelium of urinary bladder left colon epithelium of stomach mucous cell of stomach More reference expression data BioGPS More reference expression data
Gene ontology Molecular function actin binding actin filament binding Cellular component desmosome cell junction actin filament adherens junction bicellular tight junction Biological process epithelial cell morphogenesis actin filament organization actin cytoskeleton organization bicellular tight junction assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79983 69693 Ensembl ENSG00000124429 ENSMUSG00000034607 UniProt Q8WVV4 Q8K4L4 RefSeq (mRNA) NM_001307940 NM_024921 NM_181579 RefSeq (protein) NP_001294869 NP_079197 NP_853557 Location (UCSC) Chr X: 85.28 – 85.38 Mb Chr X: 111.55 – 111.61 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Protein POF1B is a protein that in humans is encoded by the POF1B gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000124429 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000034607 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Bione S, Toniolo D (Apr 2001). "X chromosome genes and premature ovarian failure". Semin Reprod Med. 18 (1): 51–7. doi:10.1055/s-2000-13475. PMID 11299520. S2CID 46587536.
6. "Entrez Gene: POF1B premature ovarian failure, 1B".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Bione S, Rizzolio F, Sala C, et al. (2005). "Mutation analysis of two candidate genes for premature ovarian failure, DACH2 and POF1B". Hum. Reprod. 19 (12): 2759–66. doi:10.1093/humrep/deh502. PMID 15459172.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
• Lacombe A, Lee H, Zahed L, et al. (2006). "Disruption of POF1B Binding to Nonmuscle Actin Filaments Is Associated with Premature Ovarian Failure". Am. J. Hum. Genet. 79 (1): 113–9. doi:10.1086/505406. PMC 1474115. PMID 16773570.

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Misplaced Pages by expanding it.

• v
• t
• e

• Genes on human chromosome X
• Human chromosome X gene stubs