PSG5 - Misplaced Pages

Protein-coding gene in the species Homo sapiens

PSG5

Identifiers

PSG5, FL-NCA-3, PSG, pregnancy specific beta-1-glycoprotein 5

External IDs

OMIM: 176394; GeneCards: PSG5; OMA:PSG5 - orthologs

Gene location (Human)

Chr.	Chromosome 19 (human)

Band	19q13.31	Start	43,166,256 bp
Band	19q13.31	End	43,186,536 bp

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

placenta

decidua

buccal mucosa cell

testicle

stromal cell of endometrium

endothelial cell

gonad

cardia

germ cell

male germ cell

n/a

More reference expression data

BioGPS


More reference expression data

Gene ontology
Molecular function	protein binding
Cellular component	extracellular region
Biological process	female pregnancy
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


5673


n/a

Ensembl


ENSG00000204941


n/a

UniProt


Q15238


n/a

RefSeq (mRNA)


NM_001130014 NM_002781


n/a

RefSeq (protein)


NP_001123486 NP_002772


n/a

Location (UCSC)

Chr 19: 43.17 – 43.19 Mb

n/a

PubMed search

n/a

Wikidata

View/Edit Human

Pregnancy-specific beta-1-glycoprotein 5 is a protein that in humans is encoded by the PSG5 gene.

References

^ GRCh38: Ensembl release 89: ENSG00000204941 – Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Khan WN, Hammarstrom S (Jul 1989). "Carcinoembryonic antigen gene family: molecular cloning of cDNA for a PS beta G/FL-NCA glycoprotein with a novel domain arrangement". Biochem Biophys Res Commun. 161 (2): 525–35. doi:10.1016/0006-291X(89)92631-4. PMID 2735907.
"Entrez Gene: PSG5 pregnancy specific beta-1-glycoprotein 5".

Panzetta-Dutari GM, Bocco JL, Reimund B, et al. (1993). "Nucleotide sequence of a pregnancy-specific beta 1 glycoprotein gene family member. Identification of a functional promoter region and several putative regulatory sequences". Mol. Biol. Rep. 16 (4): 255–62. doi:10.1007/BF00419665. PMID 1454058. S2CID 7303287.
Thompson J, Koumari R, Wagner K, et al. (1990). "The human pregnancy-specific glycoprotein genes are tightly linked on the long arm of chromosome 19 and are coordinately expressed". Biochem. Biophys. Res. Commun. 167 (2): 848–59. CiteSeerX 10.1.1.655.1870. doi:10.1016/0006-291X(90)92103-7. PMID 1690992.
Chan WY, Zheng QX, McMahon J, Tease LA (1991). "Characterization of new members of the pregnancy-specific beta 1-glycoprotein family". Mol. Cell. Biochem. 106 (2): 161–70. doi:10.1007/BF00230182. PMID 1922019. S2CID 21581759.
Thompson JA, Mauch EM, Chen FS, et al. (1989). "Analysis of the size of the carcinoembryonic antigen (CEA) gene family: isolation and sequencing of N-terminal domain exons". Biochem. Biophys. Res. Commun. 158 (3): 996–1004. CiteSeerX 10.1.1.657.2780. doi:10.1016/0006-291X(89)92821-0. PMID 2537643.
Oikawa S, Inuzuka C, Kuroki M, et al. (1989). "A pregnancy-specific beta 1-glycoprotein, a CEA gene family member, expressed in a human promyelocytic leukemia cell line, HL-60: structures of protein, mRNA and gene". Biochem. Biophys. Res. Commun. 163 (2): 1021–31. doi:10.1016/0006-291X(89)92324-3. PMID 2789512.
Teglund S, Zhou GQ, Hammarström S (1995). "Characterization of cDNA encoding novel pregnancy-specific glycoprotein variants". Biochem. Biophys. Res. Commun. 211 (2): 656–64. doi:10.1006/bbrc.1995.1862. PMID 7794280.
Olsen A, Teglund S, Nelson D, et al. (1995). "Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region". Genomics. 23 (3): 659–68. doi:10.1006/geno.1994.1555. PMID 7851895.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Blanchon L, Nores R, Gallot D, et al. (2006). "Activation of the human pregnancy-specific glycoprotein PSG-5 promoter by KLF4 and Sp1". Biochem. Biophys. Res. Commun. 343 (3): 745–53. doi:10.1016/j.bbrc.2006.03.032. PMID 16563348.
Okazaki S, Sekizawa A, Purwosunu Y, et al. (2007). "Placenta-derived, cellular messenger RNA expression in the maternal blood of preeclamptic women". Obstetrics and Gynecology. 110 (5): 1130–6. doi:10.1097/01.AOG.0000286761.11436.67. PMID 17978129. S2CID 24566450.

This article on a gene on human chromosome 19 is a stub. You can help Misplaced Pages by expanding it.

Categories:

References

Further reading