PSV may refer to:
- Partial specific volume
- PlayStation Vita, a handheld game console produced by Sony Computer Entertainment
- Petit Saint Vincent, an island south of St. Vincent in the Grenadine islands
- Platform supply vessel, a specific type of ship
- Police Support Volunteer, the rank of a volunteer performing civilian and usually office based work for British Police Forces
- Pressure safety valve
- Pressure Support Ventilation, a form of pressure cycled ventilation that gives a patient a set pressure of air at every breath initialization but has no respiratory rate set
- PSV Eindhoven, a football club from Eindhoven, Netherlands
- PSV (women), a women's football team representing PSV Eindhoven in the Eredivisie Vrouwen
- PSV Nickerie, a football club from Nieuw Nickerie, Suriname
- Public service vehicle, a bus
- Private Security Vehicle Garuda Vega, a fictional ship in the 2017 Indian Telugu-language film PSV Garuda Vega
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