PDN may refer to:
Digital
- PDN Gateway (Packet Data Network Gateway),
- PDN Mail, electronic messaging developed by Prime Computer
- Public data network
- Paint.NET
File extension
- Portable Draughts Notation (.PDN), the standard computer format for recording draughts games
- .PDN, the native format for the graphics editing program Paint.NET
Publication
- Pacific Daily News, a newspaper based on Guam
- Photo District News, US publication for photographers
Entity
- Department of Physiology, Development and Neuroscience, University of Cambridge
- National Democratic Party (Argentina) (Partido Demócrata Nacional)
Other
- ISO 639:pdn or Podena language, spoken in Indonesia
- Phenotypic disease network (PDN)
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